Quetiapine
NHS information about the medicine quetiapine, including what it's used for, who can take it, how to take it and side effects.
What quetiapine is for
Quetiapine is a medicine called an antipsychotic.
It can be used to:
- treat schizophrenia
- treat or prevent symptoms of bipolar disorder, including low mood (depression) and high mood (mania)
It can also be used, along with other medicines, to treat severe depression.
How to take quetiapine
Quetiapine usually comes as tablets that you swallow. There's also a liquid (oral suspension).
How much you need to take depends on why you're taking it.
You'll usually start on a low dose, which will be increased over the first few days. It may then be adjusted until you find a dose that works for you.
When taking quetiapine:
- take it once or twice a day with or without food – follow your doctor's advice about how and when to take it
- swallow tablets whole with a glass of water (do not split, chew or crush them)
- if you're taking liquid quetiapine, follow the instructions that come with the medicine about how to measure out the right amount
Always check the packet or leaflet that comes with your medicine. Ask a pharmacist or doctor for advice if you're not sure how to take it or have any problems taking it.
Side effects of quetiapine
Like all medicines, quetiapine can cause side effects, although not everyone gets them.
Common side effects
Common side effects of quetiapine include:
- dry mouth
- dizziness
- constipation
- a fast heartbeat
- drowsiness, tiredness and problems sleeping
- feeling irritated or agitated
- missed or irregular periods
- shaking, muscle stiffness or difficulty moving
- putting on weight
If you feel sleepy, dizzy or drowsy after taking quetiapine, do not drive, ride a bike or use machinery until you no longer have these symptoms.
More about side effects
These are not all the side effects of quetiapine.
For a full list, see the leaflet inside your medicines packet, or search for your medicine leaflet on the electronic medicines compendium website.
You can report any side effects you get on the Yellow Card Scheme website
Who can and cannot take quetiapine
Most adults can take quetiapine.
It's not usually recommended for children and young people under the age of 18. But children aged 12 to 17 may sometimes be given it under the supervision of a doctor.
Quetiapine is not suitable for everyone. For example, you may not be able to take it if:
- you've had an allergic reaction to quetiapine in the past
- you or someone in your family has a heart condition, such as a heart rhythm problem or a weak heart
- you have certain conditions, such as low blood pressure, a liver problem, or diabetes
- you've had a seizure (fit) in the past
- you have a history of alcohol or drug misuse
Before taking quetiapine, tell your doctor if you have any medical conditions.
Breastfeeding and quetiapine
Tell your doctor if you're breastfeeding.
Quetiapine can be used while breastfeeding but your baby will be regularly checked.
Possible side effects your baby may get if you're taking quetiapine and breastfeeding include:
- irritability
- drowsiness
- not gaining weight as expected
It's rare for breastfed babies to get any side effects of medicines you're using, but speak to a healthcare professional or call NHS 111 if you have any concerns about your baby.
Pregnancy and quetiapine
Tell your doctor if you're pregnant, planning to get pregnant, or you get pregnant while taking quetiapine.
Quetiapine can be used during pregnancy if needed. Your doctor will talk to you about the risks and benefits of taking it while you're pregnant.
If you need to take quetiapine while you're pregnant, your doctor will prescribe the lowest possible effective dose.
Your baby's growth may be checked more often than usual during your pregnancy. You'll also usually be advised to give birth in hospital so you and your baby can be closely monitored after you've given birth.
Taking quetiapine with other medicines, food and drink
There are some medicines, remedies and supplements that may not mix well with quetiapine including:
- certain medicines used to treat heart conditions
- certain medicines used to treat HIV
- antibiotics, such as erythromycin and clarithromycin
- antifungal medicines, such as clotrimazole and fluconazole
- nefazodone for treating depression
Before taking quetiapine, tell your doctor if you're taking any other medicines, herbal remedies, vitamins or supplements.
Food, drink and alcohol with quetiapine
Do not drink grapefruit juice while taking quetiapine.
You can drink alcohol, but it's best not to drink too much because it can make you sleepy.
Find out more about your medicine
To find out more about your medicine, you can:
- check the leaflet that comes with it
- search for your medicine leaflet on the electronic medicines compendium website
- speak to a pharmacist or doctor for advice
